A Study on the Effect of Vitamin E on Histomorphological and Immunohistochemical Changes Induced By Electromagnetic Field
hanafy, M., El-shaer, N., El Attar, A., arafa, M. (2019). A Study on the Effect of Vitamin E on Histomorphological and Immunohistochemical Changes Induced By Electromagnetic Field. EKB Journal Management System, 11(1), 85-99. doi: 10.21608/eajbsz.2019.30681
Magda S. hanafy; Nahla H. El-shaer; Amany El Attar; Manar H arafa. "A Study on the Effect of Vitamin E on Histomorphological and Immunohistochemical Changes Induced By Electromagnetic Field". EKB Journal Management System, 11, 1, 2019, 85-99. doi: 10.21608/eajbsz.2019.30681
hanafy, M., El-shaer, N., El Attar, A., arafa, M. (2019). 'A Study on the Effect of Vitamin E on Histomorphological and Immunohistochemical Changes Induced By Electromagnetic Field', EKB Journal Management System, 11(1), pp. 85-99. doi: 10.21608/eajbsz.2019.30681
hanafy, M., El-shaer, N., El Attar, A., arafa, M. A Study on the Effect of Vitamin E on Histomorphological and Immunohistochemical Changes Induced By Electromagnetic Field. EKB Journal Management System, 2019; 11(1): 85-99. doi: 10.21608/eajbsz.2019.30681

A Study on the Effect of Vitamin E on Histomorphological and Immunohistochemical Changes Induced By Electromagnetic Field

Egyptian Academic Journal of Biological Sciences, B. Zoology
Article 9, Volume 11, Issue 1, June 2019, Page 85-99  XML PDF (1.22 MB)
Document Type: Original Article
DOI: 10.21608/eajbsz.2019.30681
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Authors
Magda S. hanafy1; Nahla H. El-shaer2; Amany El Attar1; Manar H arafa3
1Department of Physics, branch of Biophysics Faculty of Science Zagazig University, Egypt
2Zoology Department, Faculty of Science, Zagazig University, Egypt
3Department of forensic medicine & toxicology, Faculty of Medicine, Zagazig University, Egypt.
Abstract
Background: Electromagnetic fields has increased gradually due to technology expansion and thus continues exposure to it may affect the biological system, so that the present work aimed to study the biological effect of non-ionizing radiation magnetic field from power line of 50 Hz which caused by devices become widely used in human activity on the structural properties of cerebral cortex and the possible protective role of vitamin E on it  through the histopathological and immunohistochemical  study  .
Result: Thirty mice were divided into three groups, group I  (control) , group II animals of this group exposed to extremely low frequency magnetic field (ELF – MF) generated  by electrical device (2mT- 20G)  for a total  period 45 day(2h/day)  and  group III exposed to the same field and period after adding vitamin E (200 mg /kg) B.W. along with  the drinking water. The results showed many changes such as neuronal degeneration and apoptosis in number of Purkinje cells and showing a decreased reactivity in carbohydrates , protein ,DNA and Glial Fibrillary Acidic Protein (GFAP)  content in (MF) treated group as compared to control , such  changes showed improvement of the histolomorpholigical and immunohistochemical changes in magnetic field (MF) and vitamin E treated group. 
Conclusion: Electromagnetic fields exposure led to degenerative changes on cerebellar cortex, and the data collected from histopathological and immunohistochemical  study  revealed  a protective effect of vitamin E on  cellular cortex layers of the cerebellar cortex 
Keywords
magnetic field; Vitamin E; (GFAP); carbohydrates; DNA; protein
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