Prevalence of thrombocytosis in epidermolysis bullosa patients
El sayed, R., Mahmoud, S., Alkhmale, M., Al-Shammari, I., Bakawi, A. (2023). Prevalence of thrombocytosis in epidermolysis bullosa patients. EKB Journal Management System, 2(1), 85-88. doi: 10.21608/ijtar.2023.140535.1004
Rasha Aly El sayed; Sanaa Mahmoud; Madiha Alkhmale; Ibtisam Al-Shammari; Amani Bakawi. "Prevalence of thrombocytosis in epidermolysis bullosa patients". EKB Journal Management System, 2, 1, 2023, 85-88. doi: 10.21608/ijtar.2023.140535.1004
El sayed, R., Mahmoud, S., Alkhmale, M., Al-Shammari, I., Bakawi, A. (2023). 'Prevalence of thrombocytosis in epidermolysis bullosa patients', EKB Journal Management System, 2(1), pp. 85-88. doi: 10.21608/ijtar.2023.140535.1004
El sayed, R., Mahmoud, S., Alkhmale, M., Al-Shammari, I., Bakawi, A. Prevalence of thrombocytosis in epidermolysis bullosa patients. EKB Journal Management System, 2023; 2(1): 85-88. doi: 10.21608/ijtar.2023.140535.1004

Prevalence of thrombocytosis in epidermolysis bullosa patients

International Journal of Theoretical and Applied Research
Volume 2, Issue 1, June 2023, Page 85-88  XML PDF (409.37 K)
Document Type: Brief Communications Arising and Corrections
DOI: 10.21608/ijtar.2023.140535.1004
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Authors
Rasha Aly El sayed email orcid 1; Sanaa Mahmoud2; Madiha Alkhmale3; Ibtisam Al-Shammari4; Amani Bakawi5
1cairo, egypt
2zoology Department, Faculty of Science, Beni Suef University
3Hail, faculty of Science
4Zoology Department, Faculty of Science, Hail Univ., Saudi Arabia
5Hail
Abstract
Epidermolysis bullosa (EB) is a rare inherited genetic disease characterized by extreme fragility of the skin and mucous membranes, which gives rise to the formation of blisters and ulcers following minor trauma. As EB is a rare disease, the reported studies regarding epidermolysis bullosa are very limited. This study was aimed to investigate the alterations in the hematologic parameters and assess the prevalence of thrombocytosis in children suffering from EB. Eight EB patients aged (3 to 12 years) from the Dermatology Unit of King Khalid Hospital (KKH), Hail city, Saudi Arabia were included in this study.
The hematological changes of EB patients were characterized by a significant decrease in the total erythrocytes (RBCs) count, hemoglobin (Hb), hematocrits (PCV) percentage, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH). The predominance of thrombocytosis and lymphocyte production was verified in this study. Moreover, Staphylococcus aureus and Streptococcus epidermidis were the most isolated microorganisms from wound cultures of EB patients. In conclusion, thrombocytosis, anemia, and/or poor nutritional status seem to be common complications in nearly all cases of EB.
Keywords
Epidermolysis bullosa; hematologic parameters; thrombocytosis; anemia
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