EFFECT OF VITAMIN D DEFICIENCY ON HYPERTROPHIC SCARRING: A meta-analysis. | ||||
Fayoum University Medical Journal | ||||
Volume 13, Issue 2, April 2024, Page 76-85 PDF (381.93 K) | ||||
Document Type: Review Articles | ||||
DOI: 10.21608/fumj.2024.252978.1291 | ||||
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Author | ||||
samira abd- elkawey ahmed ![]() | ||||
dermatology at fayoum university | ||||
Abstract | ||||
Background: : Vitamin D is a fat soluable vitamin which is vital for different systems of the human body including endocrine and immune systems, endothelial function and wound healing. Patients and methods: This meta-analysis follows the PRISMA flow diagram. The study asses the relationship between vitamin D deficiency and hypertrophic scar incidence and determine vitamin D replacement therapy effect on hypertrophic scar width and scale in patients who have deficiency in vitamin D. Result: After the search and screening, one study was eligible for our meta-analysis. Results of meta-analysis shows that scar improvement occurred significantly with p value < 0.05 after vitamin D replacement in group (1) and this was represented by low level of Vancouver score but scar width did not change after treatment in both study groups. Conclusion: Our study may provide evidence that Vitamin D supplement may be used like an adjuvent treatment for hypertrophic scars as it reduce vascularity, pliability, pigmentation, and height of scars with little effect on scar width. Keywords: Vitamin D – hypertrophic scarring. | ||||
Keywords | ||||
Vitamin D; hypertrophic; scarring | ||||
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