A Comparative Study between the Combined Effect of Frankincense and Myrrh versus the Effect of Triamcinolone Acetonide on Healing of Induced Labial Mucosal Ulcer in Albino Rats | ||||
| Al-Azhar Dental Journal for Girls | ||||
| Article 2, Volume 4, Issue 4, October 2017, Page 339-345 PDF (374.01 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/adjg.2017.5281 | ||||
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| Authors | ||||
| Abeer Wahba1; Mona Farid2; Heba Adawy3 | ||||
| 1Demonistrator of Oral and Dental Biology, Faculty of Dental Medicine for Girls, Al- Azhar University. | ||||
| 2Professor and Head of Oral and Dental Biology Department, the Former Dean of Faculty of Dental Medicine for Girls, Al- Azhar University. | ||||
| 3Assistant Professor of Oral and Dental Biology, Faculty of Dental Medicine for Girls, Al- Azhar University. | ||||
| Abstract | ||||
| Aim: The aim of the present study was to evaluate the combined effect of frankincense and myrrh versus the effect of triamcinolone acetonide (TA) on healing of induced labial mucosal ulcer in albino rats histologically and mmunohistochemically. Materials and Methods: Seventy five adult male albino rats (weighting 200-250) were used in the study and exposed to induced ulcers in the labial mucosa. The rats were divided into four groups, positive control group, group I, and three experimental groups. Negative control group: group II: (received no treatment). Group III: ulcers were treated with triamcinolone acetonide three times daily. Group IV: ulcers were treated with combination of frankincence and myrrh three times daily. Histological, immunohistochemical examination (using cyclin D1) and statistical analysis were performed for all groups. The animals were sacrificed at day 1, 3 and day 7 postoperatively. Results: Frankincense and myrrh enhanced the healing of labial mucosal ulcer better than triamcinolone acetonide. Conclusion: This study showed that combination of frankincense and myrrh have superior healing properties on oral ulcer and enhancing cell proliferation compared to triamcinolone acetonide. | ||||
| Keywords | ||||
| Wound healing; frankincense; Myrrh; Triamcinolone acetonide | ||||
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