Salivary Levels of α-Amylase & Cortisol In Patients With Recurrent Aphthous Ulceration | ||
| Egyptian Dental Journal | ||
| Article 29, Volume 64, Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), July 2018, Pages 2391-2397 PDF (455.76 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/edj.2018.76816 | ||
| Authors | ||
| Gihane Gharib Madkour1; Ibrahim El Refaie2 | ||
| 1Associate Professor of Oral Medicine, Diagnosis and Periodontology, Faculty of Dentistry, Cairo University, Egypt. | ||
| 2Lecturer of Oral Medicine, Diagnosis and Periodontology, Faculty of Dentistry, Cairo University, Egypt. | ||
| Abstract | ||
| Objective: Psychological stress is one of the prime triggering factors for recurrent aphthous ulceration. The goal of this investigation is to measure salivary levels of α-Amylase and Cortisol, as stress biomarkers, in patients with recurrent aphthous ulceration. Subjects and Methods: Whole unstimulated salivary samples were collected from 25 patients with recurrent aphthous ulceration & 25 healthy controls. Salivary levels of α-Amylase and Cortisol was quantified using enzyme-linked immunosorbent assay (ELISA). Results: A statistically significant increase in salivary levels of both α-Amylase and Cortisol was detected in recurrent aphthous ulceration patients compared to healthy controls. Conclusion: Salivary α-Amylase and Cortisol can be used as reliable stress biomarkers in patients with recurrent aphthous ulceration. | ||
| Keywords | ||
| Recurrent aphthous ulceration; salivary α-amylase; salivary Cortisol; psychological stress | ||
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