Biological Effect of Green Tea on Hypercholesterolemia Level in Rats | ||||
| Journal of Food and Dairy Sciences | ||||
| Article 2, Volume 03, Issue 3, 2018, Page 7-12 PDF (8.68 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jfds.2018.77746 | ||||
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| Authors | ||||
| Gehan A. A. Ghoniem; M. T. Shalaby; A. Z. Kh. Elias | ||||
| Food. Industries Dept., Faculty of Agriculture Mansoura University | ||||
| Abstract | ||||
| The present study is conducted to evaluate the preventive effects of green tea (Camellia sinensis) on rat feed on high fat diet. Twenty-four male albino rats each weighing 100±30g, was divided into 4 groups. Group (1) negative control group feeding basal diet, Group(2)positive control group fed in high fat diet , Group (3) hypercholesterolemic rats fed on basal diet containing 10% green tea and Group (4) hypercholesterolemic rats fed on basal diet containing tablets atorvastatin. At the end of experiment, the four groups were compared in terms of the proportion of fat in the blood. The results indicated that, high fat diet caused deleterious metabolic effects, including hypertriglyceridemia, and liver dysfunction. Rats fed high fat diet alone showed increased activities of hepatocellular enzymes in plasma, significant decline in antioxidants, and elevated lipid peroxidation indices in liver. Green tea treatment significantly reduced elevated lipid peroxidation product, and brought back the liver antioxidants and the over accumulation lipids in serum towards normal. In addition, results showed that green tea significantly reduced total cholesterol (TC), plasma triglyceride (TG), LDL-C, VLDL-C and elevated plasma antioxidant in green tea treated rats groups (3) compared to group (2). Therefore, the results are clearly indicative of the beneficial effects of green tea in reducing lateral side effects of hyperlipidemia. | ||||
| Keywords | ||||
| High fat fed diet; Green tea (Camellia sinensis); Hyperlipidemia and Hepatic statuses | ||||
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