A Comparative Study Between Transplantation of Conjunctival Limbal Autograft with Mitomycin C and Amniotic Membrane Transplantation with Mitomycin C in Recurrent Pterygium | ||||
| NILES journal for Geriatric and Gerontology | ||||
| Article 1, Volume 3, Geriatric ophthalmology, May 2020, Page 1-7 PDF (781.56 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/niles.2020.27388.1011 | ||||
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| Authors | ||||
mohammed AbdElKhalek  ; Waleed M Mahran; Safaa A Aboud
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| Ophthalmology Department, Faculty of Medicine, Beni-Suef University, Egypt | ||||
| Abstract | ||||
| Introduction : Pterygium, a wing‐shaped encroachment of the cornea by the conjunctiva, Conjunctival limbal autograft with stem cell (CLAU) or amniotic membrane transplantation (AMT) has been widely adopted in the management of pterygium. Purpose: To compare the efficacy and the complications of conjunctival limbal autograft (CLAU) with mitomycin C 0.2 % and amniotic membrane transplantation (AMT) with mitomycin C 0.2 % for treatment of recurrent pterygium Subject and methods: 80 eyes of 60 patients clinically diagnosed with recurrent pterygium were divided into two groups , group A included 40 eyes underwent pterygium excision and MMC 0.2% with CLAU , group B included 40 eyes underwent pterygium excision and MMC 0.2% with AMT . Recurrence was defined as fibrovascular tissue extension of more than one mm onto the cornea in the area of previously excised pterygium. Mean follow up period 8±1 month . Recurrence was compared in each group by using ӽ2 test Results: No major postoperative complications occurred during 6-9 months of follow-up . In CLAU group (A)only 5 eyes of recurrence occur(12.5%)after 7 months of follow up . Recurrence occur in 12 eyes (30%)in AMT group (B) after 6 months ( P value =0.043, ӽ2 test).The operated site was look like the normal adjacent site in 77%of the non recurrence group A versus 10% in group B Conclusion: CLAU with MMC is more effective than AMT with MMC for treatment of recurrent pterygium and the final cosmetic appearance is more acceptable in CLAU group than AMT group B . | ||||
| Keywords | ||||
| Recurrent; pterygium; AMT; limbal graft | ||||
| References | ||||
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