A:Recent advances in ambient electrospray ionization technologies
Amer, S., Zarad, W., El Gendy, H., Abdel Salam, R., Hadad, G., Emara, S., Masujima, T. (2020). A:Recent advances in ambient electrospray ionization technologies. EKB Journal Management System, 4(2), 24-31. doi: 10.21608/rpbs.2020.25150.1056
Sara M Amer; Walaa Zarad; Heba El Gendy; Randa Abdel Salam; Ghada Hadad; Samy Emara; Tsutoma Masujima. "A:Recent advances in ambient electrospray ionization technologies". EKB Journal Management System, 4, 2, 2020, 24-31. doi: 10.21608/rpbs.2020.25150.1056
Amer, S., Zarad, W., El Gendy, H., Abdel Salam, R., Hadad, G., Emara, S., Masujima, T. (2020). 'A:Recent advances in ambient electrospray ionization technologies', EKB Journal Management System, 4(2), pp. 24-31. doi: 10.21608/rpbs.2020.25150.1056
Amer, S., Zarad, W., El Gendy, H., Abdel Salam, R., Hadad, G., Emara, S., Masujima, T. A:Recent advances in ambient electrospray ionization technologies. EKB Journal Management System, 2020; 4(2): 24-31. doi: 10.21608/rpbs.2020.25150.1056

A:Recent advances in ambient electrospray ionization technologies

Records of Pharmaceutical and Biomedical Sciences
Article 3, Volume 4, Issue 2, July 2020, Page 24-31  XML PDF (564.43 K)
Document Type: Mini-reviews
DOI: 10.21608/rpbs.2020.25150.1056
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Authors
Sara M Amer email orcid 1; Walaa Zarad2; Heba El Gendy2; Randa Abdel Salamorcid 3; Ghada Hadadorcid 4; Samy Emara5; Tsutoma Masujima6
1Misr International University Canal Suez Universiry
2Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Misr International University, Cairo, Egypt
3pharmaceutical analytical chemistry, faculty of pharmacy, Suez Canal University,Ismailia, Egypt
4Analytical Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.
5Faculty of Pharmacy - MIU University
6RIKEN, Single Cell Mass Spectrometry Lab, Osaka, Japan
Abstract
Mass spectrometry is one of the most powerful techniques for detection and identification. Due to its sensitivity and selectivity, exact mass of analytes, and in effect, their relative fragments, allow for total structure information. As so, mass spectrometry has now played a major role in branches such as forensics, academic research, environmental studies, and manufacturing quality control. The most recent technological advances have not been to the body of the mass spectrometer, but rather to the first step only, the ion source. The ionization mechanism has been found to impact a plethora analytical results including, but not limited to, the target analytes to be ionized, the relation between sensitivity and ionization efficiency, and the sample inlet flux in relation to analysis time. This mini review focuses on the latest technologies in ambient ionization of mass spectrometry including desorption electrospray ionization, paper spray ionization, laser ablation electrospray ionization, and direct nano-electrospray ionization.
Keywords
ambient electrospray ionization; desorption electrospray ionization; paper spray ionization; laser ablation electrospray ionization; direct nano-electrospray ionization
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